Wednesday, November 21, 2018

Factors Leading to Acquired Bacterial Resistance Due to Antibiotics in Pakistan (CTBM)- Lupine Publishers




Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria change in response to the use of these medicines. Bacteria, not humans or animals, become antibiotic-resistant. Antibiotic resistance occurs when an antibiotic has lost its ability to effectively control or kill bacterial growth. Antibiotic resistance is a major concern of overuse of antibiotics. In other words bacteria are resistant and are able to multiply in the presence of therapeutic levels of an antibiotic.Antibiotic resistance has become a major issue in the 21st century and is posing as a major blip on the danger radar. Pakistan being one of only three polio-suffering countries is also suffering from bacterial resistance caused by poor use of Antibiotics. Being a third world country, Pakistan suffers from avoidable causes of antibiotic resistance but lacks the basic necessities which provides favorable environment to bacteria and produce resistance to its killer/inhibitor. Following article focuses primarily on the factors leading to acquired bacterial resistance to Antibiotics in Pakistan
 


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Antifungal Properties of Some Essential Oils against Saccharomyces cerevisiae (CTBM)-Lupine Publishers



To evaluate the antifungal activity of four essential oils against Saccharomyces cerevisiae in vitro, four commercial essential oils extracted from Thymus vulgaris, Echinacea Angustifolia, Rosmarinus officinalis and Salvia officinalis were tested at three different concentrations (10, 50 or 100 ppm) for their antimicrobial activity against Saccharomyces cerevisiae using well diffusion method. S.cerevisiae was least susceptible to the essential oils. The diameter of zone inhibition ranged between 0 and 3 mm. E. angustifolia, and R. officinalis oils appeared to be the most active, while T.vulgaris and S. officinalis oils exhibited most weak antifungal activity against S. cerevisiae. These findings increase the possibility of exploiting these essential oils as a safe alternative natural preservative.


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FGFR Gene Mutation and Pfeiffer Syndrome

Abstract Pfeiffer syndrome is a genetic disease caused by a defect in the FGFR-1 or FGFR-2 genes. This syndrome affects the skeleton, whet...